In this series of blogs, I discuss recent technological innovations that will be shaping the future of healthcare. In this blog post, I will be discussing genome sequencing and the potential and the ways it can impact the medical field.
In genome sequencing, scientists collect a sample of your DNA and then determine the identity of the approximately 3 billion nucleotides that compose the human genome. The very first human genome was completely sequenced in 2003 as part of the Human Genome Project, which initially started in 1990. In present day, genomic sequencing technology has significantly improved and has become more efficient; a human genome now takes a few days to be completely sequenced.
Some of the work being done in genomic sequencing includes:
- Personal genomics. This is a direct-to-consumer (DTC) approach, where companies send a kit to collect saliva from customers and then after some time send back an online report about the results. More and more companies are bringing the potential of genomic sequencing to the hand of consumers. Companies like 23andMe, Futura Genetics and Counsyl offer services that range from determining ancestral history and makeup to testing DNA for predisposition of most common diseases as well as tell wannabe parents whether they are at risk of having children with inherited diseases.
- Pharmacogenomics, which studies the variability of drug response due to genetic code. Different people have different reactions to drugs and the idea here is to develop personalized drugs that will help in drug therapy. Different companies and startups are utilizing genome sequencing in order to help patients know how drugs works in their body and any side effects that might occur. This would usually be provided to physicians who will deal with patients directly.
- Incorporation of artificial intelligence to mine tons of genetic information to further our understanding about diseases, diagnosis and treatment. Companies like Deep Genomics and IBM Watson are using A.I. to decode the gene and speed up the process of tailoring drug recommendations for different patients.
In summary, genomic information can be used to study trends in the human genome to help us understand causes of health and disease and use that for future detection of illnesses. To put it simply, this would allow use to detect thousands of individual conditions at an earlier stage rather than waiting until they become clinically apparent. We are still in the early stages of this field, thus a significant amount of investment and resources need to be committed to advance it.
Sources:
- Featured image: http://www.medlabsgenetics.com/m/home
- http://medicalfuturist.com/ten-ways-technology-changing-healthcare/
- https://techcrunch.com/2017/01/10/illumina-wants-to-sequence-your-whole-genome-for-100/
- https://www.bccresearch.com/market-research/biotechnology/top-ten-companies-dna-sequencing-bio112a.html